Usually, post-injection pain is normal and doesn’t last too long. That’s why we put all the necessary information into this article for you to self-inject properly and avoid post-injection pain. They can check to see if an underlying medical condition is the cause and discuss potential treatment options. If needed, you may reduce your risk of gynecomastia by switching medications or seeking treatment for a substance use disorder. But gynecomastia can also be a symptom of certain medical conditions that require treatment. Gynecomastia most often happens due to an imbalance of hormones — specifically testosterone and estrogen. Before proceeding, a patient must be examined by healthcare experts to determine the best HRT medications. Corticosteroids (steroids) are manufactured drugs that closely resemble cortisol, a hormone your adrenal glands produce. Stay on top of latest health news from Harvard Medical School. Benefits include practical tips to keep you healthy and vibrant, up-to-date health news explained simply and clearly, and special promo codes to use for our online courses, special reports, and more. Sign up for HEALTHBeat and receive trusted health information delivered right to your inbox. Get the latest in health news delivered to your inbox! No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. However, these supplements can interact with hormone levels, blood pressure, or other medications. Although minor fluid retention may not be uncommon, some symptoms require immediate evaluation. Gradual titration based on bloodwork and symptoms may reduce the likelihood of fluid accumulation. When estrogen levels increase, the body may retain more sodium and fluid. It is intended for general informational purposes and is not meant to be a substitute for professional medical advice, diagnosis, or treatment. Healthcare providers believe that many varicoceles are present at birth (congenital). When a valve doesn’t work the way it should, blood may build up inside the veins in your testicles. It has two flap-like structures that help blood move back toward your heart. They may cause mild discomfort, aches or pains. Varicoceles usually don’t have any symptoms. Fertility concerns are the top reason why people receive varicocele treatment. It’s possible that the temperature inside your scrotum increases due to the buildup of blood in the veins. Testosterone therapy increases bone strength and density. Recent clinical trials, which provide more accurate information compared to observational studies, have provided some comfort around both the heart and prostate cancer risks. Also testosterone is known to stimulate growth of prostate cancer in men diagnosed with the condition. Men taking testosterone replacement must be carefully monitored for prostate cancer. As surprising as it may be, women can also be bothered by symptoms of testosterone deficiency. All of this reduces the active (free) form of testosterone in the body. In fact, as men age, testosterone levels drop very gradually, about 1% to 2% each year — unlike the relatively rapid drop in estrogen that causes menopause. Women with high testosterone levels, due to either disease or drug use, may experience a decrease in breast size and deepening of the voice, in addition to many of the problems men may have. One treatment available for many of these problems is spironolactone, a special type of diuretic (water pill) that blocks the action of male sex hormones. A "feedback loop" closely regulates the amount of hormone in the blood. They travel from one organ or another place in the body, usually through the bloodstream, and affect many different bodily processes. What's more, testosterone plays other important roles in health and disease that may surprise you. Hone-affiliated medical practices are independently owned and operated by licensed physicians who provide services using the Hone telehealth platform. Some people don’t want or need treatment for gynecomastia. These conditions typically have other symptoms, not just gynecomastia. In other words, an increase in estrogen and a decrease in testosterone most often leads to gynecomastia. Estrogen also suppresses the release of testosterone. Sometimes, your provider might order further imaging tests. Your mental health is just as important as your physical health.